The towering Andes provide an awesome backdrop for the sprawling metropolis of Santiago. The population of this flat urban stage that spreads out from a compact city centre numbers more than five million. Despite this, a small town atmosphere prevails downtown where friends will more than likely meet and greet each other in the overcrowded streets and bustling walkways of the main commercial district. The city is a curious mix of skyscrapers and 19th-century European architecture, with some Spanish adobe bungalows thrown in for good measure. Threaded through this architectural tapestry are numerous green areas, busy markets, and quaint old squares. Street life is vibrant, and adding to the vibe is the presence of numerous chic sidewalk cafes, outside of which traditionally dressed women hawk their wares hoping to catch the eye of the tourists. There are also some small but impressive museums, several modern hotels, excellent restaurants and some good shopping opportunities in the Ahumada and Huerfanos pedestrian malls.

Santiago, officially Santiago de Chile, is the capital of Chile, and the center of its largest conurbation (Greater Santiago). It is situated at an elevation of 520 m (1700 ft) in the country's central valley. Although Santiago is the capital, legislative bodies meet in nearby Valparaíso. Approximately two decades of uninterrupted economic growth have transformed Santiago into one of Latin America's most sophisticated metropolitan areas, with extensive suburban development, dozens of shopping malls, and impressive high-rise architecture. The city also boasts some of Latin America's most spectacular infrastructure, such as the Santiago Metro and the sparkling new Costanera Norte, a highway system that passes below downtown and connects the Eastern and Western extremes of the city in 40 minutes. Santiago is headquarters to many important companies and is a regional financial center.